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Biotechnology Companies Involved in Regenerative Medicine

The global regenerative medicine market size is expected to reach USD 5.59 billion by 2025, according to a new report by Grand View Research, Inc.  With that being said this market could bring incredible value to shareholders of regenerative medicine companies over the next several years.  

Two regenerative medicine companies that have came across our radar include: 

BioRestorative Therapies, Inc. (OTCQB: BRTX), and Athersys, Inc. (NASDAQ: ATHX)

Now at first glance both of the companies have incredibly interesting technologies.  With BioRestorative Therapies, Inc. (OTCQB: BRTX) we noticed that the market cap of this company is so low it could very well have a lot of room to grow.  

BioRestorative Therapies, Inc. (OTCQB: BRTX)

Market Cap: $11.17M, current share price: $1.70

BioRestorative Therapies, Inc. develops therapeutic products using cell and tissue protocols, primarily involving adult stem cells. Today, BioRestorative is actively developing programs that aim to dramatically increase quality of care for both (i) chronic back pain caused by disc degeneration, as well as (ii) metabolic disorders including obesity and diabetes.

BRTX-100 is a novel product to treat damaged, degenerating discs, and is anticipated to be safer, cheaper, and more effective upon a single treatment. Specifically, BRTX-100 is an autologous stem cell product that uses your own stem cells that are harvested, cultured, and then injected directly into the affected disc to start the repair process.

To target obesity and metabolic disorders, they developed their ThermoStem® program that uses brown adipose-derived (“brown fat”) stem cells to generate new brown fat tissue. BioRestorative Therapies was one of the first companies to identify and publish data about this novel stem cell population. This population of fat is known to burn, rather than store, energy.  Elevated levels of brown fat have been demonstrated to increase metabolism and facilitate weight loss. Initial preclinical research indicates that increased amounts of activated brown fat in the body may be responsible for additional caloric burning, as well as reduced glucose and lipid levels.  

A month ago, Defined Health (a pharma and targeted scientific consulting firm) conducted an independent review of BRTX-100, which is BioRestorative Therapies, Inc. lead cell therapy candidate designed to treat chronic Lumbar Disc Disease (cLDD). As the report concluded, the Key Opinion Leaders (KOLs) reacted positively to the value proposition of BRTX-100 and scientists are optimistic that the clinical data presented to date is likely to be mirrored in future clinical investigations. If BRTX-100 were to be granted FDA approval, KOLs anticipate that it would be integrated into the standard of care for eligible cLDD patients.

Athersys, Inc. (NASDAQ: ATHX)

Market Cap: $274.53M, current share price: $1.99

Athersys, Inc., is a biotechnology company, focuses on the research and development activities in the field of regenerative medicine. Its clinical development programs are focused on treating neurological conditions, cardiovascular diseases, inflammatory and immune disorders, and pulmonary and other conditions. The company’s lead platform product includes MultiStem cell therapy, an allogeneic stem cell product, which has completed Phase II study for treating patients suffering from moderate and severe ischemic stroke; that is in Phase II clinical study for treating patients with acute myocardial infarction; and, which is in Phase I/II clinical study for treating patients with acute respiratory distress syndrome, as well as that has completed Phase I clinical study for patients suffering from leukemia or various other blood-borne cancers. It also develops MultiStem cell therapy to promote tissue repair and healing for animal patients, including those suffering from serious conditions with unmet medical need. 

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